1192278-62-8Relevant articles and documents
Palladium-catalyzed cross-coupling reaction of secondary benzylic bromides with grignard reagents
Lopez-Perez, Ana,Adrio, Javier,Carretero, Juan C.
, p. 5514 - 5517 (2009)
"Chemical Equation Presented" A mild palladium-catalyzed Kumada-Corriu reaction of secondary benzylic bromides with aryl and alkenyl Grignard reagents has been developed. In the presence of the Xantphos ligand, the undesired β-elimination pathway Is minimized, affording the corresponding cross-coupling products In acceptable to good yields. The reaction proceeds with inversion of the configuration.