1192807-29-6

Basic information

• Product Name: N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine
• Synonyms: N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine
• CAS NO: 1192807-29-6
• Molecular Weight: 384.502
• Mol File: 1192807-29-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine(1192807-29-6)
• EPA Substance Registry System: N-(4-(4-methoxyphenyl)-5-methylthiazol-2-yl)-4H-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octan]-2-amine(1192807-29-6)

Safety Data

• Hazardous Substances Data: 1192807-29-6(Hazardous Substances Data)

Upstream product

• 1192874-02-4 (2-(4-(4-methoxyphenyl)-5-methylthiazol-2-ylamino)-4H-1'-ammoniospiro[oxazole-5,3'-bicyclo[2.2.2]octane]-1'-yl)trihydroborate 
• 1192812-96-6 N-(4-(4-methoxyphenyl)-5-methylthiazol-2yl)-1H-imidazole-1-carbothioamide 
• 105512-88-7 2-amino-4-(4’-methoxyphenyl)-5-methyl-1,3-thiazole 

Relevant articles and documents

Α 7 as intranuclear hydroxynicotinic acetylcholine receptor quinuclidines compd.

PROBLEM TO BE SOLVED: To provide ligands for the nicotinic α-7 receptor used for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.SOLUTION: The disclosure provides compounds of the specified formula I, including their salts, and compositions and methods using the compounds.

QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.