1193687-88-5 Usage
Description
Ethyl (2-(4-(4-fluorobenzylcarbamoyl)-1,6-dihydro-5-hydroxy-1-methyl-6-oxopyrimidin-2-yl)propan-2-ylcarbamoyl)formate is a complex organic compound with a specific chemical structure. It is an impurity found in Raltegravir Potassium (R100300), which is a potent human immunodeficiency virus (HIV) integrase inhibitor and a novel anti-AIDS drug.
Uses
Used in Pharmaceutical Industry:
Ethyl (2-(4-(4-fluorobenzylcarbamoyl)-1,6-dihydro-5-hydroxy-1-methyl-6-oxopyrimidin-2-yl)propan-2-ylcarbamoyl)formate is used as an impurity in the production of Raltegravir Potassium (R100300) for its role in the development of a potent HIV integrase inhibitor. ethyl (2-(4-(4-fluorobenzylcarbamoyl)-1,6-dihydro-5-hydroxy-1-methyl-6-oxopyrimidin-2-yl)propan-2-ylcarbamoyl)formate contributes to the fight against AIDS by being a part of the process that leads to the creation of an effective anti-AIDS drug.
The compound's specific application reason is its presence as an impurity in the synthesis of Raltegravir Potassium, which is a significant component in the development of anti-AIDS medications. Its role in the pharmaceutical industry is crucial, as it is tied to the production of a drug that has the potential to help countless individuals affected by HIV and AIDS.
Check Digit Verification of cas no
The CAS Registry Mumber 1193687-88-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,3,6,8 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1193687-88:
(9*1)+(8*1)+(7*9)+(6*3)+(5*6)+(4*8)+(3*7)+(2*8)+(1*8)=205
205 % 10 = 5
So 1193687-88-5 is a valid CAS Registry Number.
1193687-88-5Relevant articles and documents
A newfangled synthesis of integrase inhibitor drug substance raltegravir potassium
Rao, S. Venkat,Potluri, Vamsi Krishna,Potluri, Ramesh Babu
, p. 2618 - 2622 (2019)
Raltegravir sodium synthesis was achieved from its one of the key starting materials with retro synthetic approach, in which without using its critical starting material chemically known as 5-methyl-1,3,4-oxadiazole-2-carbonyl chloride and which is more unstable during the synthesis of raltegravir potassium. Almost all the existed literatures commonly using this starting material in its synthesis even it is having a stability issue and hence to achieve a stable and economically viable synthesis. The current research describes a new route of synthesis by constructing an oxadiazole ring in a retro synthetic manner.
