1194757-37-3

Basic information

• Product Name: (2S,3S)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester
• Synonyms: (2S,3S)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester
• CAS NO: 1194757-37-3
• Molecular Weight: 254.243
• Mol File: 1194757-37-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(1194757-37-3)
• EPA Substance Registry System: (2S,3S)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid ethyl ester(1194757-37-3)

Safety Data

• Hazardous Substances Data: 1194757-37-3(Hazardous Substances Data)

Upstream product

• 5872-76-4 (2RS,3RS)-3-hydroxy-2-(4-nitro-benzylidenamino)-3-(4-nitro-phenyl)-propionic acid ethyl ester 
• 75414-82-3 ethyl 2-diazo-3-(4-nitrophenyl)-3-oxopropanoate 

Downstream Products

• 5872-74-2 (2RS,3RS)-2-amino-3-hydroxy-3-(4-nitro-phenyl)-propionic acid 
• 71115-69-0 erythro-2-amino-1-(p-nitrophenyl)-1,3-propanediol 
• 119-62-0 (1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 

Relevant articles and documents

An enantioselective synthesis of nitrogen protected 3-arylserine esters

A method for the preparation of (2R,3S) nitrogen protected arylserine esters is described. The method consists of rhodium mediated insertion of tert-butylcarbamate into the corresponding 3-keto-2-diazoester, affording the N-protected α-amino-β-ketoester, followed by asymmetric reduction/dynamic resolution to afford the corresponding N-protected 3-arylserine esters in good chemical yield, and in most cases high enantiomeric excess.