119520-49-9

Basic information

• Product Name: 3-phenyl-N-(3-pyridinyl)propanamide
• Synonyms: 3-phenyl-N-(3-pyridinyl)propanamide
• CAS NO: 119520-49-9
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 226.27376
• Mol File: 119520-49-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-phenyl-N-(3-pyridinyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-N-(3-pyridinyl)propanamide(119520-49-9)
• EPA Substance Registry System: 3-phenyl-N-(3-pyridinyl)propanamide(119520-49-9)

Safety Data

• Hazardous Substances Data: 119520-49-9(Hazardous Substances Data)

Upstream product

• 119541-41-2 3-Phenyl-N-pyridin-3-yl-thiopropionimidic acid pyridin-2-yl ester 
• 462-08-8 pyridin-3-ylamine 
• 2021-28-5 ethyl dihydrocinnamate 
• 501-52-0 3-Phenylpropionic acid 
• 645-45-4 hydrocinnamic acid chloride 
• 119520-57-9 N-(4-nitrophenyl)-3-phenylpropionamide 
• 28048-94-4 2-methylpropyl 3-phenypropionate 

Downstream Products

• 645-45-4 hydrocinnamic acid chloride 
• 119520-61-5 3-phenylpropanoic dithioperoxyanhydride 
• 119520-57-9 N-(4-nitrophenyl)-3-phenylpropionamide 
• 114050-31-6 3-Phenyl-propionic acid 2-thioxo-2H-pyridin-1-yl ester 
• 28048-94-4 2-methylpropyl 3-phenypropionate 
• 501-52-0 3-Phenylpropionic acid 
• 77078-54-7 3-phenylthiopropionic acid 

Relevant articles and documents

Boric Acid Catalyzed Direct Amidation between Amino-Azaarenes and Carboxylic Acids

A novel and facile boric acid catalyzed direct amidation between amino-azaarene compounds and carboxylic acids has been developed. The amidation proceeded cleanly and provided good to excellent yields of the desired amides. Boric acid is a green and inexpensive catalyst. We have also found that N,N,N′,N′-tetramethylpropane-1,3-diamine acted as an additive accelerating this boric acid catalyzed amidation. A mixed acid anhydride is postulated to be the active intermediate responsible for this successful amidation. This direct amidation is an atom- and step-economical reaction.

THE INVENTION OF RADICAL REACTIONS PART XVIII. A CONVENIENT SOLUTION TO THE 1-CARBON PROBLEM (R-CO2H --> R-13CO2H)

Radicals generated by photolysis (W light) of esters derived from N-hydroxy-2-thiopyridone react with electrophilic isocyanides 2a and (in the presence of trifluoroacetic acid) 2b to give adducts of type 3.Convenient reaction procedures have been worked out to hydrolyse the adducts to amides of type 5, from which the original acid can be regenerated under mild conditions.The three important acids oleic, linoleic and arachidonic have all given smooth reactions.In suitable examples, quantitative evolution of carbon dioxide and incorporation of 13C without dilution have been demonstrated.This reaction sequence will be useful for the labelling in the carboxyl group of prostaglandins, leukotrienes, and the side chain carboxyls of peptides.