1196153-99-7

Basic information

• Product Name: 5-chloro-thiazolo[5,4-b]pyridin-2-ylamine
• Synonyms: 5-chloro-thiazolo[5,4-b]pyridin-2-ylamine;6-Chloro-thiazolo[5,4-b]pyridin-2-ylamine
• CAS NO: 1196153-99-7
• Molecular Formula: C6H4ClN3S
• Molecular Weight: 186
• Mol File: 1196153-99-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-chloro-thiazolo[5,4-b]pyridin-2-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-thiazolo[5,4-b]pyridin-2-ylamine(1196153-99-7)
• EPA Substance Registry System: 5-chloro-thiazolo[5,4-b]pyridin-2-ylamine(1196153-99-7)

Safety Data

• Hazardous Substances Data: 1196153-99-7(Hazardous Substances Data)

Upstream product

• 90902-83-3 3-amino-2-bromo-5-chloropyridine 
• 21427-62-3 2,5-dichloro-3-nitropyridine 
• 17356-08-0 thiourea 

Downstream Products

• 159870-89-0 C₆H₂Cl₂N₂S 

Relevant articles and documents

BICYCLIC COMPOUNDS FOR DIAGNOSIS AND THERAPY

The present invention relates to the compounds of formula (I) that can be employed in the diagnosis, monitoring of disease progression or monitoring of drug activity, of a group of disorders and abnormalities associated with alpha-synuclein (a-synuclein, A- synuciein, aSynuciein, A-syn, a-syn, aSyn) aggregates including, but not limited to, Lewy bodies and/or Lewy neurites, such as Parkinson's disease. The instant compounds are particularly useful in determining a predisposition to such a disorder, monitoring residual disorder, or predicting the responsiveness of a patient who is suffering from such a disorder to the treatment with a certain medicament. The present compounds can also be used to treat, alleviate or prevent a disorder or abnormality associated with alpha-synuclein aggregates.

THIAZOLO [5, 4-B] PYRIDINE AND OXAZOLO [5, 4-B] PYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS

Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.