119665-45-1

Basic information

• Product Name: 4-(4-methylphenyl)-N,N-dimethylthiazol-2-amine
• Synonyms: 4-(4-methylphenyl)-N,N-dimethylthiazol-2-amine
• CAS NO: 119665-45-1
• Molecular Weight: 218.323
• Mol File: 119665-45-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(4-methylphenyl)-N,N-dimethylthiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-methylphenyl)-N,N-dimethylthiazol-2-amine(119665-45-1)
• EPA Substance Registry System: 4-(4-methylphenyl)-N,N-dimethylthiazol-2-amine(119665-45-1)

Safety Data

• Hazardous Substances Data: 119665-45-1(Hazardous Substances Data)

Upstream product

• 6972-05-0 1,1-dimethyl-2-thiourea 
• 22535-04-2 p-methylphenylacetyl bromide 
• 6097-27-4 2-thiocyanato-1-(4-tolyl)ethanone 
• 124-40-3 dimethyl amine 
• 10511-03-2 dimethylammonium acetate 

Downstream Products

• 119665-48-4 2-dimethylamino-5-nitroso-4-p-tolylthiazole 

Relevant articles and documents

Substituted 2-Aminothiazoles from α-Thiocyanato-acetophenones and Dialkylamines

α-Thiocyanato-acetophenones 1 react with dialkylammonium salts of weak acids (acetates, propionates, benzoates) to give 2-dialkylamino-4-aryl-thiazoles 4.As reaction medium aliphatic alcohols (methanol, ethanol), dipolar-aprotic solvents (acetonitrile, di

Spectrometric and Chemical Studies of 5-Acyl- and 5-Nitroso-2-(N,N-disubstituted Amino)thiazoles

The conformational preferences of 2-(N,N-disubstituted amino)thiazoles having a 4-substituent (R1) and a 5-acyl group (R2CO) have been established by i.r. spectrometry and a crystallographic examination.In solution the compounds with R2=aryl and R1=Me or aryl exist predominantly or entirely in the carbonyl O,S-anti arrengement; for those with R1=aryl and R2=Me the syn rotamer is the main form but a small amount (ca. 15percent) of the anti rotamer is present.Nitrosation of 4-aryl-2-dimethylaminothiazoles gives 5-nitoso derivatives, and these are probably the first authentic nitrosothiazoles.The barrier to rotation of the dimethylamino group is unexpectedly high (ΔG(excit.)298=69 kJ mol-1), exceeding even that of the 5-trifluoroacetyl analogous.