1197356-39-0

Basic information

• Product Name: 4-amino-2-(4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazin-1-yl)pyrimidine-5-carbonitrile
• Synonyms: 4-amino-2-(4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazin-1-yl)pyrimidine-5-carbonitrile
• CAS NO: 1197356-39-0
• Molecular Weight: 439.476
• Mol File: 1197356-39-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-amino-2-(4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazin-1-yl)pyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-amino-2-(4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazin-1-yl)pyrimidine-5-carbonitrile(1197356-39-0)
• EPA Substance Registry System: 4-amino-2-(4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazin-1-yl)pyrimidine-5-carbonitrile(1197356-39-0)

Safety Data

• Hazardous Substances Data: 1197356-39-0(Hazardous Substances Data)

Upstream product

• 35387-93-0 3-iodo-4-methoxy-benzoic acid methyl ester 
• 1197356-29-8 tert-butyl 4-(4-methoxy-3-(pyridin-2-ylethynyl)benzoyl)piperazine-1-carboxylate 
• 1945-84-2 2-ethynylpyridine 
• 94741-69-2 4-amino-2-chloropyrimidine-5-carbonitrile 

Relevant articles and documents

PIPERAZINE METABOTROPIC GLUTAMATE RECEPTOR 5 (MGLUR5) NEGATIVE ALLOSTERIC MODULATORS FOR ANXIETY/DEPRESSION

The present teachings relate to piperazine metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulators having Formula (I); wherein the constituent variables are as defined herein. The present teachings further relate to methods for the preparation of the compounds, and to methods for using the compounds for treatment of diseases and disorders including schizophrenia, paranoia, depression, manic-depressive illness and anxiety.