119741-58-1Relevant articles and documents
Alkylation of 3(5)-cyano-1H-pyrazole-4-carboxylic acid esters
-
, (2008/06/13)
The present invention provides a process for selectively alkylating pyrazoles comprising reacting a 3(5)-cyano-1H-pyrazole-4-carboxylic acid ester with a C4 -C8 alkene, or a C5 -C6 cycloalkene substituted at the 1-position with a C1 -C4 alkyl group, and a strong acid in a solvent which contains a strong electron withdrawing group. Also provided are new 3(5)-cyano-1H-pyrazole-4-carboxylic acid ester useful as starting materials in the process of the invention.