119771-23-2

Basic information

• Product Name: (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid
• Synonyms: (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid; Exit [Product Synonyms] (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid;EOS-61314;N-(tert-Butoxycarbonyl)-4-(dihydroxyboryl)-L-phenylalanine;4-Borono-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine
• CAS NO: 119771-23-2
• Molecular Formula: C₁₄H₂₀BNO₆
• Molecular Weight: 309.1227
• Mol File: 119771-23-2.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid(119771-23-2)
• EPA Substance Registry System: (S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoicacid(119771-23-2)

Safety Data

• Hazardous Substances Data: 119771-23-2(Hazardous Substances Data)

Usage

General Description

"(S)-3-(4-boronophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid" is a multifaceted chemical compound containing boron and phenyl groups. It is characterized as having an amino group that is linked to a tert-butoxycarbonyl unit and a propanoic acid moiety. The S- configuration of this compound indicates its stereochemistry, i.e., its three-dimensional arrangement of the atoms in it. Besides, the presence of a boronophenyl group in this compound suggests that it may have significant chemical properties significant in the field of organic chemistry, and perhaps, medicinal chemistry. However, specific detailed information about its properties, uses, or its function in chemical reactions is not readily discernible from its name alone.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 76410-58-7 p-borono-L-phenylalanine 
• 220587-29-1 methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propanoate 
• 688-74-4 boric acid tributyl ester 
• 103882-09-3 N-Boc-4-I-Phe-OH 
• 7732-18-5 water 

Downstream Products

• 76410-58-7 p-borono-L-phenylalanine 
• 850322-12-2 (4-(2S)-3-amino-2-[(tert-butoxycarbonyl)amino]-3-oxopropylphenyl)boronic acid 
• 401906-13-6 (2S)-2-(t-butoxycarbonylamino)-3-[4-(1-methyluracil-3-yl)phenyl] propionic acid 
• 1033804-86-2 (S)-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid 
• 224824-22-0 (S)-(4-(2-((tert-butoxycarbonyl)amino)-3-methoxy-3-oxopropyl)phenyl)boronic acid 
• 1246210-45-6 {4-[(2S)-2-[(tert-butoxycarbonyl) amino]-3-(dimethylamino)-3-oxopropyl]phenyl}boronic acid 
• 862854-52-2 2-tert-butoxycarbonylamino-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid 
• 554418-91-6 (2S)-2-[(tert-butoxycarbonyl)amino]-3-[4-(3-oxo-2(3H)-isoquinolinyl)phenyl]propionic acid 
• 850316-61-9 tert-butyl [(1S)-2-((1S)-2-amino-1-[4-(2-tert-butyl-1,1-dioxido-3-oxoisothiazolidin-5-yl)benzyl]-2-oxoethylamino)-1-benzyl-2-oxoethyl]carbamate 
• 850315-11-6 N-(tert-butoxycarbonyl)-L-phenylalanyl-4-(2-tert-butyl-1,1-dioxido-3-oxo-2,3-dihydroisothiazol-5-yl)-L-phenylalaninamide 
• 850322-13-3 tert-butyl (1S)-2-amino-1-[4-(2-tert-butyl-1,1-dioxido-3-oxo-2,3-dihydroisothiazol-5-yl)benzyl]-2-oxoethylcarbamate 
• 910606-99-4 3-[4-(2-tert-butyl-1,1,3-trioxo-1λ⁶-isothiazolidin-5-yl)-phenyl]-2-{2-[2-(4-methoxy-phenyl)-acetylamino]-3-phenyl-propionylamino}-N-pentyl-propionamide 
• 910606-98-3 3-[4-(2-tert-butyl-1,1,3-trioxo-1λ⁶-isothiazolidin-5-yl)-phenyl]-2-{2-[2-(4-methoxy-phenyl)-acetylamino]-3-phenyl-propionylamino}-N-pentyl-propionamide 
• 850315-77-4 (2S)-3-[4-(2-tert-butyl-1,1,3-trioxo-2,3-dihydroisothiazol-5-yl)phenyl]-2-[((2S)-2-{[(4-methoxyphenyl)acetyl]amino}-3-phenylpropanoyl)amino]-N-pentylpropanamide 

Relevant articles and documents

METHOD FOR PREPARING L-BPA

Provided is a method for preparing L-BPA, which includes steps of: reacting N-protected (S)-4-halophenylalanine of Formula I, a boronating agent, Grignard reagent and bis(2-methylaminoethyl)ether to obtain a reaction mixture, wherein the reaction mixture comprises N-protected (S)-4-boronophenylalanine of Formula II and the R2 group represents a protecting group; isolating the N-protected (S)-4-boronophenylalanine from the reaction mixture; and deprotecting the R2 group of the N-protected (S)-4-boronophenylalanine to obtain L-BPA, wherein the L-BPA has a structure of Formula III.

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