119813-70-6Relevant articles and documents
REGIOSELECTIVE MONO-ADDITION OF LITHIUM ENOLATES TO N-CARBAMOYL-L-PYROGLUTAMATES
Ohta, Tomihisa,Kimura, Toshihiko,Sato, Nobuaki,Nozoe, Shigeo
, p. 4303 - 4304 (2007/10/02)
Regioselective mono-addition of lithium enolate of esters to N-carbamoyl-L-pyroglutamates (1) gave excellent yields of (2S)-5-oxoamino acid derivatives (2) which were found to be an effective synthon for syntheses of carbapenams and carbapenems.