119836-85-0Relevant articles and documents
Phosphine-catalyzed Aza-MBH reactions of vinylpyridines: Efficient and rapid access to 2,3,5-triarylsubstituted 3-pyrrolines
Chen, Jing,Li, Jianjun,Wang, Jiazhe,Li, Hao,Wang, Wei,Guo, Yuewei
, p. 2214 - 2217 (2015)
Vinylpyridines have been developed in aza-Morita-Baylis-Hillman (MBH) reaction to construct triarylsubstituted 3-pyrrolines. The first electron-deficient aromatic ring is marked as an activating mode for the vinyl group in the MBH reaction. This method provides efficient and rapid access to a range of triarylpyrrolines in good yields and at an excellent level of diastereoselectivity. Moreover, the synthetic potential of this protocol is further enhanced by the straightforward synthesis of unsymmetrical tri- and polyarylsubstituted pyrroles.
INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
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Paragraph 0130, (2016/01/29)
no abstract published
Substituted Heteroaromatic Pyrazole-Containing Carboxamide and Urea Compounds as Vanilloid Receptor Ligands
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, (2013/03/26)
Substituted heteroaromatic pyrazole-containing carboxamide and urea compounds as vanilloid receptor ligands, pharmaceutical compositions containing these compounds and also to a method of using these compounds for treating and/or inhibiting pain and further diseases and/or disorders.