119842-40-9

Basic information

• Product Name: N-[1-(4-Methoxy-phenyl)-vinyl]-formamide
• Synonyms: N-[1-(4-Methoxy-phenyl)-vinyl]-formamide
• CAS NO: 119842-40-9
• Molecular Weight: 177.203
• Mol File: 119842-40-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[1-(4-Methoxy-phenyl)-vinyl]-formamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-(4-Methoxy-phenyl)-vinyl]-formamide(119842-40-9)
• EPA Substance Registry System: N-[1-(4-Methoxy-phenyl)-vinyl]-formamide(119842-40-9)

Safety Data

• Hazardous Substances Data: 119842-40-9(Hazardous Substances Data)

Upstream product

• 128828-10-4 C₁₆H₁₇NOS 
• 2258-42-6 formyl acetic anhydride 
• 625-55-8 isopropyl formate 
• 917-54-4 methyllithium 
• 874-90-8 4-methoxybenzonitrile 
• 2475-92-5 4-methoxyacetophenone oxime 

Downstream Products

• 851330-27-3 7-methoxy-1-(4-methoxyphenyl)naphthalene 
• 119842-49-8 1-(1-isocyanovinyl)-4-methoxybenzene 

Relevant articles and documents

Direct Conversion of Nitriles into Alkene “Isonitriles”

The sequenced addition of RLi to nitriles, trapping with isopropylformate, and dehydration with phosphoryl chloride provides an efficient, direct synthesis of alkene isocyanides. The one-pot sequence involves a series of carefully orchestrated steps: addition, formylation, tautomerization, and dehydration, with CuCN catalyzing a key equilibration of a formyl imine to an N-formyl enamine. The resulting aromatic alkeneisocyanides, that are otherwise challenging to synthesize, engage in an unusual [4+2]-type cycloaddition/1,3-H shift/decyanation sequence to afford substituted naphthalenes.

REDUCTIVE FORMYLATION OF OXIMES; AN APPROACH TO THE SYNTHESIS OF VINIL ISONITRILES

Reduction of ketoximes using anhydrous titanium-(III)-acetate in the presence of mixed formic-acetic anhydride yields N-formyl enamines whichmay be dehydrate to vinyl isonitriles