1198565-08-0

Basic information

• Product Name: N-(4-fluorophenyl)-1H-indole-1-carboxamide
• Synonyms: N-(4-fluorophenyl)-1H-indole-1-carboxamide
• CAS NO: 1198565-08-0
• Molecular Weight: 254.264
• Mol File: 1198565-08-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-fluorophenyl)-1H-indole-1-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-fluorophenyl)-1H-indole-1-carboxamide(1198565-08-0)
• EPA Substance Registry System: N-(4-fluorophenyl)-1H-indole-1-carboxamide(1198565-08-0)

Safety Data

• Hazardous Substances Data: 1198565-08-0(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 65141-04-0 phenyl N-(4-fluorophenyl)carbamate 
• 1195-45-5 para-fluorophenyl isocyanate 
• 1198564-97-4 C₁₅H₁₁FN₂O 

Relevant articles and documents

Copper(I)-Catalyzed N-Carboxamidation of Indoles with Isocyanates: Facile and General Method for the Synthesis of Indole-1-carboxamides

A facile and general method for the synthesis of indole-1-carboxamides was developed via copper(I)-catalyzed N-carboxamidation of indoles with isocyanates under mild reaction conditions. This process is scalable and tolerates a wide spectrum of indoles and isocyanates to deliver corresponding products in good to excellent yields, providing a viable synthetic approach to indole-1-carboxamides, which can be used for the treatment of inflammatory diseases and diabetes.

Gold-catalyzed intramolecular hydroamination of terminal alkynes in aqueous media: efficient and regioselective synthesis of indole-1-carboxamides

Using [Au(PPh3)]Cl/Ag2CO3-catalyzed 5-endo-dig cyclization in water under microwave irradiation, we developed a fast and green route to prepare indole-1-carboxamides from N′-substituted N-(2-alkynylphenyl)ureas. The descri