1198587-13-1Relevant articles and documents
Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells
Ishii, Yuta,Hattori, Yoshiyuki,Yamada, Toshiharu,Uesato, Shinichi,Maitani, Yoshie,Nagaoka, Yasuo
experimental part, p. 4603 - 4610 (2009/12/26)
We developed histone deacetylase inhibitor (HDACI) prodrugs to enhance the expression of the external genes transfected into human cells with cationic nanoparticles (NPs). We synthesized five kinds of lipid-linked HDACI prodrugs in which n-dodecanoic acid