120041-56-7Relevant articles and documents
Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation
Liang, Dongdong,Yu, Wenbo,Nguyen, Nam,Deschamps, Jeffrey R.,Imler, Gregory H.,Li, Yue,MacKerell, Alexander D.,Jiang, Chao,Xue, Fengtian
, p. 3589 - 3596 (2017)
We report a novel synthesis of phenanthridinones from N-methoxybenzamides using an oxidative C-H amidation reaction at room temperature in open air with modest to excellent yields. This method demonstrated unprecedented substrate scope. In particular, it solved the long-standing challenge in the synthesis of phenanthridinones with sterically demanding substitutions.