120155-05-7

Basic information

• Product Name: 7-benzyloxy-6-methoxy-1-methylene-2-nicotinyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 7-benzyloxy-6-methoxy-1-methylene-2-nicotinyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 120155-05-7
• Molecular Weight: 386.45
• Mol File: 120155-05-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-benzyloxy-6-methoxy-1-methylene-2-nicotinyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-benzyloxy-6-methoxy-1-methylene-2-nicotinyl-1,2,3,4-tetrahydroisoquinoline(120155-05-7)
• EPA Substance Registry System: 7-benzyloxy-6-methoxy-1-methylene-2-nicotinyl-1,2,3,4-tetrahydroisoquinoline(120155-05-7)

Safety Data

• Hazardous Substances Data: 120155-05-7(Hazardous Substances Data)

Upstream product

• 54-86-4 sodium nicotinate 
• 10400-19-8 3-pyridinecarbonyl chloride 
• 78867-50-2 7-(benzyloxy)-6-methoxy-1-methyl-3,4-dihydroisoquinoline 

Downstream Products

• 115757-50-1 11-benzyloxy-10-methoxy-7,8-dihydro-5H-benzopyrido<3,4-g>quinolizin-5-thione 
• 120155-02-4 11-benzyloxy-10-methoxy-7,8-dihydro-5H-benzopyrido<3,2-g>quinolizin-5-one 
• 104669-20-7 11-benzyloxy-10-methoxy-7,8-dihydro-5H-benzopyrido<3,4-g>quinolizin-5-one 

Relevant articles and documents

STUDIES ON INDIAN MEDICINAL PLANTS : PART 91 - STRUCTURE AND SYNTHESIS OF ALAMARIDINE. A NOVEL 5-METHYLBENZOPYRIDOQUINOLIZINE ALKALOID FROM ALANGIUM LAMARCKII

The structure of alamaridine (1), a novel benzopyridoquinolizine alkaloid, was established by spectral data.However, its stereochemistry could only be determined now by a total synthesis involving the key cyclisation of an 1-methyl-2-pyridylmethyl-3,4-dihydroisoquinolinium salt 19a in presence of pivaloyl chloride and triethylamine.O-Benzyldehydroalamaridine thus formed was reduced by sodium cyanoborohydride and then deprotected to obtain alamaridine (1) and 5-epi-alamaridine (26).Isoalamaridine (27) and its 5-epimer (28) were also synthesised following the same route.