120158-16-9Relevant articles and documents
Asymmetric Reduction of α-(Dimethylthiocarbamoylthio) Carbonyl Compounds with Bakers' Yeast
Tsuboi, Sadao,Kohara, Noriyuki,Doi, Katsumi,Utaka, Masanori,Takeda, Akira
, p. 3205 - 3210 (1988)
Treatment of α-(dimethythiocarbamoylthio) ketones with bakers' yeast afforded the corresponding chiral alcohols in high yields with high enentiomeric excess (in most cases, more than 96 percent ee). α- (Dimethylthiocarbamoylthio) aldehydes were reduced to give chiral α-(dimethylthiocarbamoylthio) alcohols in 69-92 percent yields with 32-63 percent ee, which were converted to chiral 1,2-epitio derivatives.