1201908-18-0Relevant articles and documents
Novel biphenylcarboxylic acid peroxisome proliferator-activated receptor (PPAR) δ selective antagonists
Kasuga, Jun-ichi,Ishida, Seiichi,Yamasaki, Daisuke,Makishima, Makoto,Doi, Takefumi,Hashimoto, Yuichi,Miyachi, Hiroyuki
scheme or table, p. 6595 - 6599 (2010/06/14)
We designed and synthesized novel PPARδ antagonists based on the crystal structure of the PPARδ full agonist TIPP-204 bound to the PPARδ ligand-binding domain, in combination with our nuclear receptor helix 12 folding modification hypothesis. Representati