1202039-12-0

Basic information

• Product Name: (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester
• Synonyms: (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester
• CAS NO: 1202039-12-0
• Molecular Weight: 241.331
• Mol File: 1202039-12-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester(1202039-12-0)
• EPA Substance Registry System: (+)-(2R)-(2-oxopropyl)piperidine-1-carbamic acid tert-butylester(1202039-12-0)

Safety Data

• Hazardous Substances Data: 1202039-12-0(Hazardous Substances Data)

Upstream product

• 201350-80-3 (R)-tert-butyl 2-allylpiperidine-1-carboxylate 
• 1323722-74-2 N-(5-chloropentylidene)-4-methylbenzenesulfonamide 
• 505-18-0 2,3,4,5-tetrahydropyridine 
• 110-89-4 piperidine 
• 2858-66-4 (-)-pelletierine 
• 2156-71-0 N-chloropiperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 182343-60-8 2-(2-propenyl)-1-piperidinecarboxylic acid tert-butyl ester 
• 202926-14-5 tert-butyl hex-5-en-1-ylcarbamate 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 
• 86953-81-3 tert-butyl 2-hydroxypiperidine-1-carboxylate 
• 1229358-34-2 C₁₃H₂₃NO₃ 
• 675-20-7 piperidin-2-one 
• 905717-53-5 (R)-tert-butyl 2-(2-(methoxy(methyl)amino)-2-oxoethyl)piperidine-1-carboxylate 

Downstream Products

• 6152-82-5 (R)-(-)-pelletierine hydrochloride 
• 1393603-42-3 C₂₈H₃₃I₂NO₆ 
• 1393603-65-0 C₂₈H₃₃I₂NO₆ 
• 1393603-26-3 C₁₇H₂₂INO₃ 
• 1393603-37-6 (4S,9aR)-hexahydro-4-(2-(2'-methoxymethoxy-5'-carboxaldehyphenyl)-4,5-dimethoxyphenyl)-1H-quinolizin-2(6H)-one 
• 1393603-43-4 (4S,9aR)-hexahydro-4-(2-(2'-methoxymethoxy-5'-methanolphenyl)-4,5-dimethoxyphenyl)-1H-quinolizin-2(6H)-ol 
• 1393603-44-5 (4S,9aR)-hexahydro-4-(2-(2'-methoxymethoxy-5'-carboxaldehyphenyl)-4,5-dimethoxyphenyl)-1H-quinolizin-2(6H)-ol 
• 1393603-47-8 (4S,9aR)-hexahydro-4-(2-(2'-methoxymethoxy-5'-carboxaldehyphenyl)-4,5-dimethoxyphenyl)-1H-quinolizin-2yl-acrylate 
• 1393603-48-9 (4S,9aR)-hexahydro-4-(2-(2'-hydroxy-5'-carboxaldehyphenyl)-4,5-dimethoxy-phenyl)-1H-quinolizin-2yl-acrylate 
• 1393603-50-3 (4S,9aR)-hexahydro-4-(2-(2'-tert-butyldimethylsiloxy-5'-carboxaldehyphenyl)-4,5-dimethoxy-phenyl)-1H-quinolizin-2yl-acrylate 
• 1393603-51-4 (4S,9aR)-hexahydro-4-(2-(2'-tert-butyldimethylsiloxy-5'-vinylphenyl)-4,5-dimethoxyphenyl)-1H-quinolizin-2yl-acrylate 
• 1393603-33-2 C₂₉H₃₅NO₇ 
• 1393603-34-3 C₂₉H₃₇NO₇ 
• 1393603-62-7 C₃₃H₄₅NO₇Si 

Relevant articles and documents

Enantioselective Rhodium-Catalyzed Allylation of Aliphatic Imines: Synthesis of Chiral C Aliphatic Homoallylic Amines

Reported herein is a method for the efficient syntheses of optically active 1-alkyl homoallylic amines in yields up to 95%, 13.5:1 dr, and 98% ee under mild, aqueous reaction conditions, via the Rh-catalyzed asymmetric allylation of aliphatic aldimines. This method provides a streamlined synthetic platform for the preparation of indolizidine and piperidine alkaloids, thus demonstrating its usefulness.

Asymmetric catalyzed intramolecular aza-Michael reaction mediated by quinine-derived primary amines

An intramolecular organocatalytic enantioselective aza-Michael reaction of carbamates, sulfonamides and acetamides to α,β-unsaturated ketones was developed. This process is promoted by 9-amino-9-deoxy-epi-quinine and diphenyl hydrogen phosphate to afford

Straightforward access to enantioenriched 2-allylpiperidine: Application to the synthesis of alkaloids

An efficient stereocontrolled preparation of (2R,RS)-2-allyl-(N- tert-butylsulfinyl)piperidine and its enantiomer is detailed. The sequence requires only two synthetic operations with one-column chromatography and is readily scaled up. The versatility of these chiral building blocks was exemplified by the total or formal synthesis of some natural and unnatural alkaloids.