Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1202044-20-9

Post Buying Request

1202044-20-9 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1202044-20-9 Usage

Use

Ostarine, also known as?ostarine MK-2866,?is an investigational?selective androgen receptor modulator?(SARM) developed by?GTx, Inc.?for the treatment of conditions such as?muscle wasting?and?osteoporosis.

Mechanism

Ostarine(MK-2866) attaches to proteins in the body known as androgen receptors. When ostarine binds to these receptors, it tells the muscles in the body to grow. Unlike some other chemicals that bind to androgen receptors, such as?steroids, ostarine doesn't seem to cause as many side effects in other parts of the body.

Health effects

The FDA have warned that SARMs can have serious side effects ranging from risk of heart attack to stroke and liver damage.

Description

Ostarine is an investigational drug that has not yet been approved by the US Food and Drug Administration (FDA). It is part of a class of drugs called selective androgen receptor modulators (SARMs).

Uses

(2S)-3-(4-Cyanophenoxy-2,3,5,6-d4)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide is a metabolites of selective androgen receptor modulators (SARM).

Check Digit Verification of cas no

The CAS Registry Mumber 1202044-20-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,2,0,4 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1202044-20:
(9*1)+(8*2)+(7*0)+(6*2)+(5*0)+(4*4)+(3*4)+(2*2)+(1*0)=69
69 % 10 = 9
So 1202044-20-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m1/s1

1202044-20-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4

1.2 Other means of identification

Product number -
Other names (2S)-3-(4-Cyanophenoxy-2,3,5,6-d4)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1202044-20-9 SDS

1202044-20-9Synthetic route

4-cyanophenol-d4
1025089-21-7

4-cyanophenol-d4

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
206193-17-1

(2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4
1202044-20-9

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide-d4

Conditions
ConditionsYield
With sodium carbonate In acetone for 3h; Reflux;59.9%

1202044-20-9Downstream Products

1202044-20-9Relevant articles and documents

METABOLITES OF SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF

-

Page/Page column 123, (2010/01/12)

This invention provides metabolites of SARM compounds including inter alia glucuronidated metabolites and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, muscle wasting disease and/or disorder, a bone related disease and/or disorder, metabolic syndrome, diabetes and associated diseases, and others.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1202044-20-9