120225-78-7Relevant articles and documents
2-(N'-aralkylidenehydrazino)adenosines: Potent and selective coronary vasodilators
Niiya,Thompson,Silvia,Olsson
, p. 4562 - 4566 (1992)
This study aimed at the development of 2-(N'- aralkylidenehydrazino)adenosines as coronary vasodilators. The reaction of aromatic aldehydes or ketones with 2-hydrazinoadenosine in refluxing methanol formed the target compounds 2-27 as crystalline products
2-(SUBSTITUTED AMINO) ADENOSINES AS ANTIHYPERTENSIVES
-
, (2008/06/13)
Disclosed are 2-substituted adenosine derivatives of the formula STR1 in which R represents a substituted amino grouping of the formula STR2 as defined herein; pharmaceutically acceptable ester derivatives thereof in which free hydroxy groups are esterified in the form of a pharmaceutically acceptable prodrug ester; and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising said compounds; methods for their preparation; and their use in mammals as therapeutically effective adenosine-2 (A-2) agonists.