120230-88-8

Basic information

• Product Name: 3-<(p-Tolylsulfonyl)methylene>isoindolinone
• Synonyms: 3-<(p-Tolylsulfonyl)methylene>isoindolinone
• CAS NO: 120230-88-8
• Molecular Weight: 317.365
• Mol File: 120230-88-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-<(p-Tolylsulfonyl)methylene>isoindolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<(p-Tolylsulfonyl)methylene>isoindolinone(120230-88-8)
• EPA Substance Registry System: 3-<(p-Tolylsulfonyl)methylene>isoindolinone(120230-88-8)

Safety Data

• Hazardous Substances Data: 120230-88-8(Hazardous Substances Data)

Upstream product

• 132560-61-3 E-3-p-toluenesulfonylmethylidene phthalide 
• 132560-54-4 Z-p-toluenesulfonylmethylidene phthalide 
• 3185-99-7 Methyl p-tolyl sulfone 
• 132560-55-5 3-Hydroxy-3-(toluene-4-sulfonylmethyl)-3H-isobenzofuran-1-one 
• 132560-53-3 3-(p-toluenesulfonylmethylidene)phthalan 
• 87-41-2 2-benzofuran-1(3H)-one 
• 120230-87-7 1-(2-bromophenyl)-2-tosylethan-1-one 

Downstream Products

• 132560-58-8 3-p-toluenesulfonylmethylidene-isoindole-1-one 

Relevant articles and documents

Novel Lactam Synthesis by Use of a Combination System of Carbonylation and Nitrogenation

An amide unit was constructed from aryl halide and titanium-isocyanate complex prepared from TiCl4 under atmospheric pressure of molecular nitrogen and carbon monoxide in the presence of a palladium catalyst.With this combination system of carbonylation and nitrogenation, isoindolinone and quinazolinone derivatives were synthesized from o-halophenyl alkyl ketone in one step.The reaction proceeds through the oxidative addition of enol lactone, generated by palladium-catalyzed carbonylation to o-halophenyl alkyl ketone, to titanium-isocyanate complex.