1202482-66-3Relevant articles and documents
Discovery of pyrimidine benzimidazoles as Src-family selective Lck inhibitors. Part II
Zhang, Guobao,Ren, Pingda,Gray, Nathanael S.,Sim, Taebo,Wang, Xia,Liu, Yi,Che, Jianwei,Dong, Weitong,Tian, Shin-Shay,Sandberg, Mark L.,Spalding, Tracy A.,Romeo, Russell,Iskandar, Maya,Wang, Zhiliang,Seidel, H. Martin,Karanewsky, Donald S.,He, Yun
scheme or table, p. 6691 - 6695 (2010/06/12)
A series of 4-amino-6-benzimidazole-pyrimidines was designed to target lymphocyte-specific tyrosine kinase (Lck), a member of the Src-family kinases (SFKs). These type II inhibitors were optimized using a cellular Lck-dependent proliferation assay and are
