1202816-93-0 Usage
Description
4-Nitroso-N-2-pyridinylbenzenesulfonamide, also known as 4-nitrososulfopyridine, is an organic compound that serves as an intermediate in the synthesis of various chemical compounds. It is characterized by the presence of a nitroso group and a sulfonamide group attached to a pyridine ring, which contributes to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Synthesis:
4-Nitroso-N-2-pyridinylbenzenesulfonamide is used as an intermediate in the synthesis of Sulfasalazine (S699084) and its related metabolites and derivatives. Sulfasalazine is a medication used in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. 4-nitrososulfopyridine plays a crucial role in the development of new therapeutic agents and the modification of existing drugs to improve their efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 1202816-93-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,2,8,1 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1202816-93:
(9*1)+(8*2)+(7*0)+(6*2)+(5*8)+(4*1)+(3*6)+(2*9)+(1*3)=120
120 % 10 = 0
So 1202816-93-0 is a valid CAS Registry Number.
1202816-93-0Relevant articles and documents
Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives
Castrejon, J. Luis,Lavergne, Sidonie N.,El-Sheikh, Ayman,Farrell, John,Maggs, James L.,Sabbani, Sunil,O'Neill, Paul M.,Kevin Park,Naisbitt, Dean J.
, p. 184 - 192 (2011/02/16)
Exposure to sulfamethoxazole (SMX) is associated with T-cell-mediated hypersensitivity reactions in human patients. T-cells can be stimulated by the putative metabolite nitroso SMX, which binds irreversibly to protein. The hydroxylamine and nitroso deriva
