120303-62-0

Basic information

• Product Name: (4-fluorophenyl)(2-nitrophenyl)methanone
• Synonyms: (4-fluorophenyl)(2-nitrophenyl)methanone
• CAS NO: 120303-62-0
• Molecular Weight: 245.21
• Mol File: 120303-62-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (4-fluorophenyl)(2-nitrophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-fluorophenyl)(2-nitrophenyl)methanone(120303-62-0)
• EPA Substance Registry System: (4-fluorophenyl)(2-nitrophenyl)methanone(120303-62-0)

Safety Data

• Hazardous Substances Data: 120303-62-0(Hazardous Substances Data)

Upstream product

• 462-06-6 fluorobenzene 
• 10542-55-9 nitrobenzotrichloride 
• 88-72-2 1-methyl-2-nitrobenzene 
• 552-16-9 ortho-nitrobenzoic acid 
• 610-14-0 2-nitrobenzyl chloride 

Downstream Products

• 886853-85-6 1-(4-fluorophenyl)-1-(2-nitrophenyl)ethene 
• 121660-37-5 2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline 
• 121659-86-7 methyl 4-(4'-fluorophenyl)-2-cyclopropylquinoline-3-carboxylate 
• 121660-11-5 2-cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline 
• 1229609-91-9 4-(4-fluoro-phenyl)-2-phenyl-quinazoline 
• 1246763-14-3 4-(4'-fluorophenyl)quinazoline 
• 1010690-98-8 syn-(2-aminophenyl)(4-fluorophenyl)methanone oxime 
• 105189-03-5 2-[4-(3-hydroxypropyl)-1-piperazinyl]-4-(4-fluorophenyl)quinoline 
• 105188-98-5 2-[4-(2-hydroxyethyl)-1-piperazinyl]-4-(4-fluorophenyl)quinoline dihydrochloride 
• 105189-06-8 2-(4-Ethyl-piperazin-1-yl)-4-(4-fluoro-phenyl)-quinoline; hydrochloride 
• 120301-22-6 4-(4-Fluoro-phenyl)-2-(4-methyl-piperazin-1-yl)-quinoline; hydrochloride 
• 120301-18-0 2-(4-Benzyl-piperazin-1-yl)-4-(4-fluoro-phenyl)-quinoline 
• 120301-16-8 2-(1-piperazinyl)-4-(4-fluorophenyl)quinoline 
• 105189-21-7 2-chloro-4-(4-fluorophenyl)quinoline 

Relevant articles and documents

Preparation method of 2-amino-4'-fluoro-diphenyl ketone

The invention discloses a preparation method of 2-amino-4'-fluoro-diphenyl ketone. The preparation method comprises the following steps that ortho-nitrotoluene is chloridized by chlorine gas to obtainO-nitrotrichlorotoluene; then the O-nitrotrichlorotolue

Palladium-Catalyzed Carbonylative Couplings of Vinylogous Enolates: Application to Statin Structures

The first Pd-catalyzed carbonylative couplings of aryl and vinyl halides with vinylogous enolates are reported generating products derived from C-C bond formation exclusively at the γ-position. Good results were obtained with a dienolate derivative of acetoacetate (1,3-dioxin-4-one). These transformations occurred at room temperature and importantly with only stoichiometric carbon monoxide in a two-chamber reactor. The methodology was applied to the synthesis of two members of the statin family generating the cis-3,5-diol acid motif by a γ-selective carbonylation followed by a cis-stereoselective reduction of the 3,5-dicarbonyl acid intermediates.

A simple and efficient approach to the synthesis of 2-phenylquinazolines via sp3 C-H functionalization

(Figure presented) A facile and novel approach to the synthesis of 2-phenylquinazolines was developed via a tandem reaction following sp 3 C-H functionalization. Twenty-five examples of 2-phenylquinazolines were obtained from easily available 2-aminobenzophenones and benzylic amines with good to excellent yields.