120445-36-5

Basic information

• Product Name: 2-[(2-fluorophenyl)methylene]hydrazinecarboxamide
• CAS NO: 120445-36-5
• Molecular Weight: 181.169
• Mol File: 120445-36-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-[(2-fluorophenyl)methylene]hydrazinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2-fluorophenyl)methylene]hydrazinecarboxamide(120445-36-5)
• EPA Substance Registry System: 2-[(2-fluorophenyl)methylene]hydrazinecarboxamide(120445-36-5)

Safety Data

• Hazardous Substances Data: 120445-36-5(Hazardous Substances Data)

Upstream product

• 563-41-7 semicarbazide hydrochloride 
• 446-52-6 2-Fluorobenzaldehyde 
• 4426-72-6 hydrazine carboxamide 

Relevant articles and documents

Synthesis and in vitro antitumor activity of 1,3,4-oxadiazole derivatives based on benzisoselenazolone

A series of novel 1,3,4-oxadiazole derivatives based on benzisoselenazolone has been prepared and tested for antiproliferative activity in vitro against the cells of human cancer cell lines: SSMC-7721 (human liver cancer cell), MCF-7 (human breast cancer cell) and A549 (human lung cancer cell). All the compounds obtained exhibited antiproliferative activity and showed selective cytotoxicity against different cancer cells. Compounds 7d and 7i showed significant antiproliferative activities against MCF-7 cells, with IC50 values of 1.07 and 1.76/μM respectively. Compound 7d were found to be the most potent compound against SSMC-7721 cells, with IC50 values 4.46/μM.

Synthesis of 2-amino-1,3,4-oxadiazoles and 2-Amino-1,3,4-thiadiazoles via sequential condensation and I2-mediated oxidative C-O/C-S bond formation

2-Amino-substituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles were synthesized via condensation of semicarbazide/thiosemicarbazide and the corresponding aldehydes followed by I2-mediated oxidative C-O/C-S bond formation. This transition-metal-free sequential synthesis process is compatible with aromatic, aliphatic, and cinnamic aldehydes, providing facile access to a variety of diazole derivatives bearing a 2-amino substituent in an efficient and scalable fashion.

DIORGANOSILICON(IV) COMPLEXES OF FLUORO-IMINES: SYNTHETIC, SPECTROSCOPIC AND BIOLOGICAL ASPECTS

The synthetic, spectroscopic and biological studies of some diorganosilicon(IV) complexes derived from fluoroimines having NS and NO donor systems have been undertaken. The fluoroimines were prepared by the condensation of 2-Fluorobenzaldehyde and 1-(2-Fl