1204518-04-6 Usage
Description
[4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate is a chemical compound utilized as a source of electrophilic phenyliodine(III) species in organic synthesis. It is recognized for its high reactivity and capability to transfer the phenyl group to other molecules. The trifluoromethanesulfonate counterion enhances solubility and stability in organic solvents, making it a versatile reagent for various chemical reactions in the laboratory.
Uses
Used in Organic Synthesis:
[4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate is used as a reagent for the synthesis of aryl ketones, aryl ethers, and aryl alkenes due to its high reactivity and ability to transfer the phenyl group to other molecules.
Used in Laboratory Research:
[4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate is used as a source of electrophilic phenyliodine(III) species in the laboratory, often in combination with other reagents and catalysts to facilitate a range of chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate may be used as a reagent for the synthesis of complex organic molecules that are precursors to various drugs, leveraging its high reactivity and phenyl group transfer capabilities.
Used in Material Science:
[4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate may also find applications in material science, particularly in the synthesis of novel materials with specific properties, such as conductivity or magnetism, by incorporating aryl groups into their structures.
Used in Chemical Catalysts:
[4-(ethoxycarbonyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate can be used as a catalyst or a catalyst precursor in specific chemical reactions, taking advantage of its electrophilic nature and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1204518-04-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,5,1 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1204518-04:
(9*1)+(8*2)+(7*0)+(6*4)+(5*5)+(4*1)+(3*8)+(2*0)+(1*4)=106
106 % 10 = 6
So 1204518-04-6 is a valid CAS Registry Number.
1204518-04-6Relevant articles and documents
Copper-mediated trifluoromethylation of diaryliodonium salts with TMSCF3 at room temperature
Yang, Jing-Yun,Xu, Xiu-Hua,Qing, Feng-Ling
, p. 175 - 180 (2015)
A convenient method for the preparation of trifluoromethylated arenes from the reaction of diaryliodonium salts with TMSCF3 in the presence of CuBF4·(MeCN)4 and KF at room temperature within 25 min was developed. This reaction provides a valuable complement to the previously established trifluoromethylation methods.
N-Arylation of DABCO with Diaryliodonium Salts: General Synthesis of N-Aryl-DABCO Salts as Precursors for 1,4-Disubstituted Piperazines
Bugaenko, Dmitry I.,Yurovskaya, Marina A.,Karchava, Alexander V.
supporting information, p. 6389 - 6393 (2018/10/09)
Employing DABCO as a substrate, aryl(mesityl)iodonium triflates are introduced as arylating agents for a tertiary sp3-nitrogen. Mild conditions and exceptional selectivity of the aryl group transfer allow unprecedented N-aryl-DABCO salts to be obtained, bearing substituents of different electronic natures. This metal-free methodology has no analogy among known transition-metal-based reactions. The utility of isolated N-aryl-DABCO salts is demonstrated for the preparation of flibanserin.
Flow Synthesis of Diaryliodonium Triflates
Laudadio, Gabriele,Gemoets, Hannes P. L.,Hessel, Volker,No?l, Timothy
, p. 11735 - 11741 (2017/11/24)
A safe and scalable synthesis of diaryliodonium triflates was achieved using a practical continuous-flow design. A wide array of electron-rich to electron-deficient arenes could readily be transformed to their respective diaryliodonium salts on a gram scale, with residence times varying from 2 to 60 s (44 examples).
