1204579-18-9Relevant articles and documents
2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study
Thapa, Pritam,Karki, Radha,Thapa, Uttam,Jahng, Yurngdong,Jung, Mi-Ja,Nam, Jung Min,Na, Younghwa,Kwon, Youngjoo,Lee, Eung-Seok
experimental part, p. 377 - 386 (2010/04/02)
Designed and synthesized 60 2-thienyl-4-furyl-6-aryl pyridine derivatives were evaluated for their topoisomerase I and II inhibitory activities at 20 μM and 100 μM and cytotoxicity against several human cancer cell lines. Compounds 8, 9, 11-29 showed sign