1205098-82-3 Usage
Description
1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one is a chemical compound that belongs to the class of ketone derivatives, featuring a benzofuran ring in its molecular structure. 1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one holds promise in the fields of medicinal chemistry and pharmaceutical research due to its potential bioactivity and the diverse pharmacological properties associated with benzofuran compounds.
Uses
Used in Pharmaceutical Research:
1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one is used as a compound in pharmaceutical research for its potential to contribute to the development of new drugs and therapeutic agents. 1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one's molecular structure suggests that it may possess bioactive properties, which could be harnessed for various medical applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one is used as a starting material or intermediate for the synthesis of more complex molecules with potential therapeutic effects. Its benzofuran ring structure is known to be associated with a range of pharmacological properties, making it a valuable component in the design and synthesis of novel drug candidates.
Used in the Development of Therapeutic Agents:
1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one is used as a building block in the development of therapeutic agents targeting various medical conditions. 1-(2,3-dihydrobenzofuran-4-yl)ethan-1-one's potential bioactivity and the known pharmacological effects of benzofuran compounds make it a promising candidate for further research and investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 1205098-82-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,5,0,9 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1205098-82:
(9*1)+(8*2)+(7*0)+(6*5)+(5*0)+(4*9)+(3*8)+(2*8)+(1*2)=133
133 % 10 = 3
So 1205098-82-3 is a valid CAS Registry Number.
1205098-82-3Relevant articles and documents
Concise Six-Step Asymmetric Approach to Ramelteon from an Acetophenone Derivative Using Ir, Rh, Cu, and Ni Catalysis
Cluzeau, Jér?me,Nettekoven, Ulrike,Kova?evi?, Miroslav Planinc,?asar, Zdenko
, p. 2129 - 2135 (2021/10/20)
A concise six-step asymmetric synthesis of nearly enantiomerically pure ramelteon was developed from a monocyclic precursor with a 17% overall yield and a 97% ee in the asymmetric step. The synthetically challenging tricyclic 1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan core of ramelteon was assembled by using Ir-catalyzed O-vinylation and Rh-catalyzed vinyl ether annulation through directed C-H bond activation, while the chirality was introduced with enantioselective reduction of an α,β-unsaturated nitrile moiety under hydrosilylation conditions using a CuII/Walphos type catalyst. The presented methodology represents the shortest synthetic approach to ramelteon.
SYNTHESIS OF 1-(2,3-DIHYDROBENZOFURAN-4-YL)ETHANONE AS INTERMEDIATE IN THE PREPARATION OF RAMELTEON
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Page/Page column 17-18, (2010/11/03)
The present invention relates in general to the field of organic chemistry and in particular to the preparation of 1-(2,3-dihydrobenzofuran-4-yl)ethanone, an intermediate in preparation of (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, i.e. ramelteon.
SYNTHESIS OF (S)-N-[2-(1,6,7,8-TETRAHYDRO-2H-INDENO-[5,4-B]FURAN-8-YL)ETHYL]PROPIONAMIDE
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Page/Page column 21, (2010/09/03)
The present invention relates in general to the field of organic chemistry and in particular to the preparation of (S)-N-[2-(1,6,7,8-tetrahydro-2H-indeno-[5,4-b]furan-8-yl)ethyl]propionamide, i.e. ramelteon, and analogues thereof.
