120573-33-3

Basic information

• Product Name: 2-(methoxycarbonylmethylamino)-5⁽⁶⁾-benzoylbenzimidazole
• CAS NO: 120573-33-3
• Molecular Weight: 309.324
• Mol File: 120573-33-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(methoxycarbonylmethylamino)-5⁽⁶⁾-benzoylbenzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methoxycarbonylmethylamino)-5⁽⁶⁾-benzoylbenzimidazole(120573-33-3)
• EPA Substance Registry System: 2-(methoxycarbonylmethylamino)-5⁽⁶⁾-benzoylbenzimidazole(120573-33-3)

Safety Data

• Hazardous Substances Data: 120573-33-3(Hazardous Substances Data)

Upstream product

• 31431-39-7 mebendazole 
• 39070-63-8 4-benzoylbenzene-1,2-diamine 
• 52329-60-9 (2-amino-1H-benzimidazol-5-yl)(phenyl)methanone 
• 96-34-4 methyl chloroacetate 

Relevant articles and documents

Studies in Antiparasitic Agents: Part 8 - Synthesis of 2-Substitutedamino-5(6)-benzoylbenzimidazoles as Structural Analogs of Mebendazole Metabolites

The synthesis of a series of 2-substitutedamino-5(6)-benzoylbenzimidazoles (6-22) has been carried out as the structural analogs of 2-amino-5(6)-benzoyl/α-hydroxy-α-phenylmethylbenzimidazoles (3, 4), the two metabolites of mebendazole.The compounds 6-22 have been tested for their anthelmintic activity against Ancylostoma ceylanicum, Nippostrongylus brasiliensis and Hymenolepis nana in rodents.Compounds 9, 11, 12, 13 and 14 exhibit 100percent elimination of A. ceylanicum worms from the animals at a single oral dose of 50-250 mg/kg.Some of the compounds also show activity against H. nana and N. brasiliensis.