1206676-80-3

Basic information

• Product Name: 5-(2-Bromo-4,5-difluorophenyl)-1-(tert-butyl)-4-iodo-1H-pyrazole
• Synonyms: 5-(2-Bromo-4,5-difluorophenyl)-1-(tert-butyl)-4-iodo-1H-pyrazole
• CAS NO: 1206676-80-3
• Molecular Formula: C13H12BrF2IN2
• Molecular Weight: 441.0530564
• Mol File: 1206676-80-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-(2-Bromo-4,5-difluorophenyl)-1-(tert-butyl)-4-iodo-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-Bromo-4,5-difluorophenyl)-1-(tert-butyl)-4-iodo-1H-pyrazole(1206676-80-3)
• EPA Substance Registry System: 5-(2-Bromo-4,5-difluorophenyl)-1-(tert-butyl)-4-iodo-1H-pyrazole(1206676-80-3)

Safety Data

• Hazardous Substances Data: 1206676-80-3(Hazardous Substances Data)

Downstream Products

• 1246078-78-3 (R)-N-((1R)-(5-(2-bromo-4,5-difluorophenyl)-1-tert-butyl-1H-pyrazol-4-yl)(cyclopropyl)methyl)-2-methylpropane-2-sulfinamide 

Relevant articles and documents

PROCESS FOR THE PRODUCTION OF FUSED, TRICYCLIC SULFONAMIDES

The present invention provides methods, i.e., scalable or large-scale processes for the production of fused, tricyclic sulfonamido analogs, such as substituted or unsubstituted 5- (aryl-sulfonyl)-4,5-dihydro- 1H-pyrazolo[4,3-c]quinolines and 5-(heteroaryl-sulfonyl)-4,5- dihydro-1H-pyrazolo[4,3-c]quinolines. Exemplary methods of the invention include an intra-molecular cyclization step, in which a carbon-nitrogen bond is formed, and which employs a copper-based catalyst that contains at least one organic ligand, such as DMEDA. The invention further provides compounds, which are useful as intermediates in the methods of the invention.