120680-98-0

Basic information

• Product Name: 4-ethyl cinnamic acid
• Synonyms: (E)-3-(4-乙基苯基)丙烯酸
• CAS NO: 120680-98-0
• Molecular Formula: C₁₁H₁₂O₂
• Molecular Weight: 176.21178
• Mol File: 120680-98-0.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-ethyl cinnamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethyl cinnamic acid(120680-98-0)
• EPA Substance Registry System: 4-ethyl cinnamic acid(120680-98-0)

Safety Data

• Hazardous Substances Data: 120680-98-0(Hazardous Substances Data)

Upstream product

• 198341-20-7 ethyl 3‐(4‐ethylphenyl)acrylate 
• 4748-78-1 4-ethylbenzylaldehyde 
• 124-38-9 carbon dioxide 
• 870717-91-2 (E)-4,4,5,5-tetramethyl-2-(2-(4-ethylphenyl)ethenyl)-1,3,2-dioxaborolane 
• 723304-09-4 ethyl (E)-3-(4-ethylphenyl)-2-propenoate 
• 141-82-2 malonic acid 
• 67302-72-1 (4-ethyl-benzyliden)-aniline 

Downstream Products

• 57045-16-6 C₁₁H₁₁ClO 
• 1377846-50-8 C₁₁H₁₆N₂O₂ 
• 1426576-80-8 (E)-N-(4,5-dihydrothiazol-2-yl)-3-(4-ethylphenyl)acrylamide 
• 1415662-66-6 (2E)-N-1,3-benzothiazol-2-yl-3-(4-ethylphenyl)acrylamide 
• 4313-70-6 L-p-ethylphenylalanine 
• 1038997-18-0 3-[(E)-3-(4-ethylphenyl)-2-propenoyl]-2-thiazolidinethione 
• 64740-36-9 3-(4-ethyl-phenyl)-propionic acid 
• 110105-20-9 2-[(E)-3-(4-Ethyl-phenyl)-acryloylamino]-3-phenyl-propionic acid 
• 1011301-86-2 (E)-3-(4-ethylphenyl)prop-2-en-1-ol 
• 120681-08-5 (E)-4-ethylcinnamic acid chloride 

Relevant articles and documents

Carboxylation of Alkenyl Boronic Acids and Alkenyl Boronic Acid Pinacol Esters with CO2 Catalyzed by Cuprous Halide

A cuprous halide catalysed carboxylation of alkenyl boronic acids and alkenyl boronic acid pinacol esters under CO2, affording the corresponding α, β-unsaturated carboxylic acids in good yield, has been developed. The potassium (E)-trifluoro(styryl)borate is also compatible with this reaction. This simple and efficient copper(I) catalytic system showed good functional group tolerance.

Cu/Fe-Cocatalyzed Formation of β-Ketophosphonates by a Domino Knoevenagel-Decarboxylation-Oxyphosphorylation Sequence from Aromatic Aldehydes and H-Phosphonates

A domino Knoevenagel-decarboxylation-alkene difunctionalization sequence has been developed for the conversion of benzaldehydes into β-ketophosphonates, catalyzed by a cooperative Cu/Fe system, whereby CP and CO bonds are formed simultaneously in a one-pot reaction. The reaction proceeds in good yields and with a broad substrate scope and environmentally benign conditions.

Synthesis and anticancer activity of 13-membered cyclic enediynes

We herein describe the synthesis of 15 novel 13-membered cyclic enediyne derivatives using simple and straightforward approach. Representative examples were screened for their anticancer activities on 60 different human tumor cell lines representing various histologies viz. leukemia, melanoma, and cancers of lung, colon, kidney, ovary, breast, prostate, and central nervous system. The enediyne derivatives with halogen substitutions, especially fluorides were found to be active against most of the cell lines. The initial results indicates marginal to good inhibition for the growth of tumor cells for several cell lines, which shows the potential of these class of compound towards anticancer application. 15 novel 13-membered cyclic enediyne derivatives using a simple and straightforward approach are synthesized. The initial results show the potential of this class of compounds towards anticancer application. Copyright