1207164-22-4Relevant articles and documents
CoMFA studies and in vitro evaluation of some 3-substituted benzylthio quinolinium salts as anticryptococcal agents
Bolden, Sidney,Boateng, Comfort A.,Zhu, Xue Y.,Etukala, Jagan R.,Eyunni, Suresh K.,Jacob, Melissa R.,Khan, Shabana I.,Ablordeppey, Seth Y.
, p. 7194 - 7201 (2013)
The 3-dimensional quantitative structure-activity relationship (3D-QSAR) molecular modeling technique or comparative molecular field analysis (CoMFA) has been used to design analogs of the natural product cryptolepine (1). Twenty-three compounds with thei
A simple, base-free preparation of S-aryl thioacetates as surrogates for aryl thiols
Van Den Hoogenband, Adri,Lange, Jos H. M.,Bronger, Raymond P. J.,Stoit, Axel R.,Terpstra, Jan Willem
experimental part, p. 6877 - 6881 (2011/03/18)
A mild method for the preparation of S-aryl thioacetates by hetero cross-coupling reactions of aryl bromides or aryl triflates with potassium thioacetate is described. The reaction proceeded smoothly in toluene at 110°C, mediated by catalytic Pd2(dba)3 in combination with CyPF-tBu as the ligand. Neither the presence of a base nor microwave conditions were required. The formed S-aryl thioacetate proved to be stable under flash chromatographic conditions and could be rapidly converted into the corresponding thiol under mildly basic conditions.
