1207613-75-9Relevant articles and documents
α(δ')-Michael addition of alkyl amines to dimethyl (E)-hex-2- en-4-ynedioate: Synthesis of α,β-dehydroamino acid derivatives
Chavan, Arjun S.,Deng, Jie-Cheng,Chuang, Shih-Ching
, p. 2611 - 2622 (2013)
The direct nucleophilic addition of alkyl amines to the α(δ')-carbon atom of dimethyl (E)-hex-2-en-4-ynedioate to generate α,β-dehydroamino acid derivatives is reported. Herein, we have studied the reactivity of various primary and secondary alkyl amines