1207743-73-4

Basic information

• Product Name: 3-(2'-thienylcarbonyl)cyclopropane-1,1,2,2-tetracarbonitrile
• Synonyms: 3-(2'-thienylcarbonyl)cyclopropane-1,1,2,2-tetracarbonitrile
• CAS NO: 1207743-73-4
• Molecular Weight: 252.256
• Mol File: 1207743-73-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2'-thienylcarbonyl)cyclopropane-1,1,2,2-tetracarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2'-thienylcarbonyl)cyclopropane-1,1,2,2-tetracarbonitrile(1207743-73-4)
• EPA Substance Registry System: 3-(2'-thienylcarbonyl)cyclopropane-1,1,2,2-tetracarbonitrile(1207743-73-4)

Safety Data

• Hazardous Substances Data: 1207743-73-4(Hazardous Substances Data)

Upstream product

• 1885-22-9 bromomalononitrile 
• 138380-43-5 2-thiopheneglyoxal monohydrate 
• 109-77-3 malononitrile 

Relevant articles and documents

Synthesis of 2,2,3,3-tetracyanocyclopropyl ketones and their reactions with oxygen-centered nucleophiles

A procedure for the synthesis of 2,2,3,3-tetracyanocyclopropyl ketones has been developed on the basis of three-component Wideqvist reaction of dihydroxymethyl ketones, 2-bromomalononitrile, and malononitrile. The presence of five electron-withdrawing groups in the resulting cyclopropyl ketones determines high acidity of proton in the cyclopropane ring. Facile deprotonation by the action of bases promotes opening of the three-membered ring with formation of either 1,1,3,3-tetracyanopropenides or (in the presence of alcohols or oximes), [2-alkoxy(aminooxy)-5-amino-4-cyanofuran-3(2H)-ylidene] malononitriles. The reaction with acetone oxime was not accompanied by cleavage of the three-membered ring, and nucleophilic attack was directed at the cyano groups in the trans position with respect to the carbonyl group to give the corresponding (1R*,5S*,6R*)-4-amino-2,2-bis(prop-2- ylideneaminooxy)-3-azabicyclo[3.1.0]hex-3-ene-1,5-dicarbonit riles.