120781-02-4 Usage
Description
2-BROMO-3-METHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER is an organic compound that serves as an important intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its imidazole ring structure, which is a heterocyclic aromatic organic compound containing nitrogen atoms, and a methyl ester group attached to the carboxylic acid functionality.
Uses
Used in Pharmaceutical Industry:
2-BROMO-3-METHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER is used as a key intermediate in the synthesis of anti-tuberculosis drug PA-824 against M. tuberculosis. It plays a crucial role in the development of this medication, which is designed to target and eliminate the tuberculosis bacteria effectively.
In the synthesis process, 2-BROMO-3-METHYL-3H-IMIDAZOLE-4-CARBOXYLIC ACID METHYL ESTER contributes to the formation of the final drug molecule, which possesses the necessary pharmacological properties to combat tuberculosis. Its unique structure and reactivity make it a valuable component in the creation of PA-824, a drug that holds promise for the treatment of drug-resistant tuberculosis strains and improving patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 120781-02-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,7,8 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120781-02:
(8*1)+(7*2)+(6*0)+(5*7)+(4*8)+(3*1)+(2*0)+(1*2)=94
94 % 10 = 4
So 120781-02-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H7BrN2O2/c1-9-4(5(10)11-2)3-8-6(9)7/h3H,1-2H3
120781-02-4Relevant articles and documents
MALT1 MODULATORS AND USES THEREOF
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Paragraph 00120; 00184, (2021/07/10)
Provided herein are compounds, compositions, and methods useful for modulating MALT1 and for treating related diseases, disorders, and conditions.
Development of matrix metalloproteinase-13 inhibitors – A structure-activity/structure-property relationship study
Fuerst, Rita,Yong Choi, Jun,Knapinska, Anna M.,Smith, Lyndsay,Cameron, Michael D.,Ruiz, Claudia,Fields, Gregg B.,Roush, William R.
, p. 4984 - 4995 (2018/09/27)
A structure-activity/structure-property relationship study based on the physicochemical as well as in vitro pharmacokinetic properties of a first generation matrix metalloproteinase (MMP)-13 inhibitor (2) was undertaken. After systematic variation of inhi
INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING
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Page/Page column 120, (2010/02/15)
The invention relates to the inhibition of vascular endothelial growth factor (VEGF) receptor signaling and hepatocyte growth factor (HGF) receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions
