120788-68-3Relevant articles and documents
Synthesis of pyrido[2,3-d]pyrimidines via palladium-catalyzed coupling reaction followed by electrocyclic reaction
Rho, Kee Yoon,Kim, Joong Hyup,Kim, Sung Hoon,Yoon, Cheol Min
, p. 2521 - 2528 (1998)
Pyrido[2,3-d]pyrimidines (5a-h) were regioselectively synthesized by the reaction of 5-iodo-6-(dimethylaminomethylene)amino-1,3-dimethyluracil(3), which was prepared from the reaction of 6-amino-1,3-dimethyluracil with dimethylformamide dimethyl acetal followed by iodination, with various olefins (4a-h) in the presence of a catalytic amount of Pd(OAc)2, Cul, and K2CO3 in DMF at 100 °C.