120808-65-3

Basic information

• Product Name: 1,10-bis(p-tolylsulphonyl)-1,10-diazacyclo-octadecane
• Synonyms: 1,10-bis(p-tolylsulphonyl)-1,10-diazacyclo-octadecane
• CAS NO: 120808-65-3
• Molecular Weight: 562.838
• Mol File: 120808-65-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,10-bis(p-tolylsulphonyl)-1,10-diazacyclo-octadecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,10-bis(p-tolylsulphonyl)-1,10-diazacyclo-octadecane(120808-65-3)
• EPA Substance Registry System: 1,10-bis(p-tolylsulphonyl)-1,10-diazacyclo-octadecane(120808-65-3)

Safety Data

• Hazardous Substances Data: 120808-65-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 32038-98-5 N,N'-Octamethylenedibenzamide 
• 373-44-4 1,8-diaminooctan 
• 4549-32-0 1,8-dibromooctane 
• 83492-49-3 N¹,N⁸-di(p-toluenesulfonyl)-1,8-diaminooctane 

Downstream Products

• 296-30-0 1,10-Diaza-cyclooctadecan 

Relevant articles and documents

MACROHETEROCYCLES. PART 44. FACILE SYNTHESIS OF AZACROWN ETHERS AND CRYPTANDS IN A TWO-PHASE SYSTEM

A facile procedure is proposed for the preparation of azacrown ethers and cryptands by condensation of dibromides or ethylene glycol bis(toluene-p-sulphonate)s with acyclic bis(sulphonamide)s or with bisdiazacrown ethers, respectively.The reaction was carried out in a two-phase system of aqueous alkali-toluene (benzene)in the presence of quaternary ammonium salts as phase transfer catalysts.The catalytic activity decreased in the sequence: Bu4NI ca.Bu4NBr > Bu4NCl > Bu4NHSO4 > Et3NCH2C6H5NCl.Maximum yields of twelve-membered azacrown ethers are obtained when lithium hydroxide is used, while crown ethers of larger size are observed in the presence of sodium or potassium hydroxides; this may be due to a template effect.