1208109-63-0

Basic information

• Product Name: N-(p-tolyl)-1H-pyrrole-2-carboxamide
• Synonyms: N-(p-tolyl)-1H-pyrrole-2-carboxamide
• CAS NO: 1208109-63-0
• Molecular Weight: 200.24
• Mol File: 1208109-63-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(p-tolyl)-1H-pyrrole-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-tolyl)-1H-pyrrole-2-carboxamide(1208109-63-0)
• EPA Substance Registry System: N-(p-tolyl)-1H-pyrrole-2-carboxamide(1208109-63-0)

Safety Data

• Hazardous Substances Data: 1208109-63-0(Hazardous Substances Data)

Upstream product

• 109-97-7 pyrrole 
• 622-58-2 p-Tolylisocyanate 
• 634-97-9 pyrrole-2-carboxyl acid 
• 1094448-30-2 N-(2-bromo-4-methylphenyl)-1H-pyrrole-2-carboxamide 
• 5427-82-7 1H-pyrrole-2-carbonyl chloride 
• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 106-49-0 p-toluidine 

Downstream Products

• 1208109-64-1 C₃₁H₂₈N₄O₂ 
• 1344146-16-2 5-(p-tolyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-25-3 5-(p-tolyl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-20-8 5-(p-tolyl)-3-(trifluoromethyl)pyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-one 
• 1344146-22-0 8-methyl-5-(p-tolyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-23-1 9-methyl-5-(p-tolyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-21-9 7-fluoro-5-(p-tolyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-24-2 N-(4-oxo-5-(p-tolyl)-4,5-dihydropyrrolo[1,2-a]quinoxalin-7-yl)-acetamide 
• 1344146-18-4 4-oxo-5-(p-tolyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline-9-carbonitrile 
• 1344146-19-5 4-oxo-5-(p-tolyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline-7-carbonitrile 
• 1344146-17-3 7-nitro-5-(p-tolyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one 
• 1344146-27-5 5,7-di-p-tolylpyrrolo[1,2-a]pyrrolo[1',2':4,5]pyrazino[2,3-g]quinoxaline-4,8(5H,7H)-dione 
• 1344146-26-4 5-(p-tolyl)pyrido[3,2-e]pyrrolo[1,2-a]pyrazin-6(5H)-one 
• 1353565-31-7 2-(tetrahydro-2H-pyran-2-yl)-5-(p-tolyl)pyrrolo[1',2':1,6]pyrazino[2,3-d]pyridazine-1,6(2H,5H)-dione 

Relevant articles and documents

Substrate Controlled Regioselective Bromination of Acylated Pyrroles Using Tetrabutylammonium Tribromide (TBABr3)

Electrophilic bromination of pyrroles bearing carbonyl substituents at C-2 typically results in a mixture of the 4- and 5-brominated species, generally favoring the 4-position. Herein, we describe a substrate-controlled regioselective bromination in which

Synthesis of 6-substituted 2-pyrrolyl and indolyl benzoxazoles by intramolecular O-arylation in photostimulated reactions

The synthesis of a series of 6-substituted 2-pyrrolyl and 2-indolyl benzoxazoles by photostimulated C-O cyclization of anions from 2-pyrrole carboxamides, 2-indole carboxamides, or 3-indole carboxamides has been found to proceed in good to excellent yields (41-100%) in DMSO and liquid ammonia. The pyrrole and indole carboxamides are obtained in good to very good isolated yields by an amidation reaction of different 2-haloanilines with 2-carboxylic acid of pyrrole and 2- or 3-carboxylic acid of indole. To explain the regiochemical outcome of these reactions (C-O arylation vs C-N or C-C arylation), a theoretical analysis was performed using DFT methods and the B3LYP functional.