1208940-88-8Relevant articles and documents
Isolation of Ugi four-component condensation primary adducts: A straightforward route to isocoumarins
Faggi, Cristina,Garcia-Valverde, Maria,Marcaccini, Stefano,Menchi, Gloria
supporting information; experimental part, p. 788 - 791 (2010/04/06)
(Chemical Equation Presented) Ugi four-component condensation (Ugi-4CC) between 2-formylbenzoic acid, phenacylamine dimethyl acetal, and isocyanides afforded 1H-isochromen-1-ones (isocoumarins). These products, where structure corresponds to the tautomeric enediamine form of the Ugi-4CC primary adducts, were stable enough to allow their isolation and characterization. Stable isocoumarins were also obtained by employing anilines as the amino component In the Ugi four-component condensation.