1209001-69-3Relevant articles and documents
Efficient and library-friendly synthesis of furo- and thieno[2,3-d] pyrimidin-4-amine derivatives by microwave irradiation
Han, Ying,Ebinger, Katalin,Vandevier, Lauren E.,Maloney, Jennifer W.,Nirschl, David S.,Weller, Harold N.
experimental part, p. 629 - 632 (2010/04/05)
A new, divergent, efficient, and selective synthesis of furo- and thieno[2,3-d]pyrimidin-4-amine derivatives by microwave irradiation has been developed starting from readily available amines and substituted 2-aminofuran-3-carbonitrile or 2-aminothiophene-3-carbonitrile, which are converted into corresponding formamidines in DMF using benzenesulfonyl chloride.