1210935-33-3 Usage
Description
(R)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE, also known as (3R)-1-Methyl-3-Pyrrolidinemethanol, is an organic compound with a unique structure that features a hydroxymethyl group and a methylpyrrolidine ring. It is characterized by its potential applications in the pharmaceutical and chemical industries due to its versatile chemical properties.
Uses
Used in Pharmaceutical Industry:
(R)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE is used as a reactant for the synthesis of heterocyclic carboxylic acid amides. These compounds have potential as PDK1 inhibitors, which are important targets for the development of new therapeutics in the treatment of various diseases, including cancer and metabolic disorders.
Used in Chemical Synthesis:
(R)-3-(HYDOXYMETHYL)-1-METHYLPYRROLIDINE is used as a building block in the synthesis of various complex organic molecules. Its unique structure allows for the creation of a wide range of compounds with diverse applications in different industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1210935-33-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,0,9,3 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1210935-33:
(9*1)+(8*2)+(7*1)+(6*0)+(5*9)+(4*3)+(3*5)+(2*3)+(1*3)=113
113 % 10 = 3
So 1210935-33-3 is a valid CAS Registry Number.
1210935-33-3Relevant articles and documents
Preparation method of chiral 3-substituted pyrrolidine derivative
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, (2020/11/01)
The invention provides a preparation method of a chiral 3-substituted pyrrolidine derivative. The preparation method comprises an intermediate preparation step, a diastereomer mixture preparation step, a chiral separation step and a chiral 3-substituted pyrrolidine derivative synthesis step. According to the invention, through catalytic asymmetric kinetic resolution, a mixture of two diastereoisomers is efficiently converted into a diastereoisomer with a certain single configuration, chiral separation is realized, a key intermediate is obtained with high yield, and a series of chiral 3-substituted pyrrolidine derivatives are synthesized. The whole reaction route is mild in reaction condition, simple and convenient to operate, high in resolution efficiency, high in atom economy, low in costand suitable for industrial scale production.
