121105-92-8Relevant articles and documents
Pyridazines with Heteroatom Substituents in Position 3 and 5. 2 . Regioselective Introduction of Mercapto Groups in Pyridazines
Olesen, Preben H.,Kappe, Thomas
, p. 1719 - 1723 (2007/10/02)
The nucleophilic substitution of halogen in 3,5-dichloro-6-phenylpyridazine 1, 5-chloro-2-methyl-6-phenylpyridazin-3(2H)-one 13 as well as in 3-chloro-2-methyl-6-phenylpyridazin-5(2H)-one 14 with methoxy, ethoxy, and the 2-methyl-2-propanethiolate anion is described.In the last type of compounds the t-butylthio groups can be eliminated regioselectively with Lewis acids, resulting in the formation of monomercapto and monothiopyridazines.