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1211523-68-0

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1211523-68-0 Usage

Description

5-(difluoromethyl)pyridin-2-amine is an organic compound characterized by the presence of a pyridine ring with an amine group at the 2nd position and a difluoromethyl group at the 5th position. This molecule is known for its potential applications in the pharmaceutical and chemical industries due to its unique structural features and reactivity.

Uses

Used in Pharmaceutical Industry:
5-(difluoromethyl)pyridin-2-amine is used as a reactant for the preparation of uracil derivatives, which serve as Mer-Axl inhibitors. These inhibitors play a crucial role in the development of novel therapeutic strategies for various diseases, including cancer, by targeting the Mer-Axl signaling pathway. The incorporation of the difluoromethyl group in the molecule enhances its potency and selectivity as an inhibitor, making it a valuable component in the synthesis of such pharmaceutical agents.

Check Digit Verification of cas no

The CAS Registry Mumber 1211523-68-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,1,5,2 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1211523-68:
(9*1)+(8*2)+(7*1)+(6*1)+(5*5)+(4*2)+(3*3)+(2*6)+(1*8)=100
100 % 10 = 0
So 1211523-68-0 is a valid CAS Registry Number.

1211523-68-0Downstream Products

1211523-68-0Relevant articles and documents

MODULATORS OF THE INTEGRATED STRESS PATHWAY

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Page/Page column 227, (2019/05/22)

Provided herein are compounds of formula (I) and (II), compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

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