1211939-75-1

Basic information

• Product Name: (S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate
• Synonyms: (S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate
• CAS NO: 1211939-75-1
• Molecular Weight: 452.237
• Mol File: 1211939-75-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate(1211939-75-1)
• EPA Substance Registry System: (S)-methyl 4-(2-amino-2-oxoethyl)-2-(4-bromo-2-fluorobenzyl)-1,3-dioxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-carboxylate(1211939-75-1)

Safety Data

• Hazardous Substances Data: 1211939-75-1(Hazardous Substances Data)

Downstream Products

• 147254-64-6 ranirestat 

Relevant articles and documents

A concise enantioselective synthesis of (-)-ranirestat

Chemical Equation Presented A concise enantioselective synthesis of the potent aldose reductase inhibitor ranirestat (1) is reported. The synthesis was accomplished employing inexpensive, commercially available starting materials. A palladium-catalyzed asymmetric allylic alkylation (Pd-AAA) of malonate 4 was utilized as a key transformation to construct the tetrasubstituted chiral center in the target.