121250-04-2 Usage
Description
(R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID, also known as (R)-Trifluorolactic Acid, is a chiral compound that exists as a stereoisomer of (S)-Trifluorolactic Acid. It is characterized by its unique molecular structure, which includes a trifluoromethyl group and a hydroxyl group attached to a chiral carbon. (R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID is of interest in various fields due to its potential applications and properties.
Uses
Used in Chiral Derivatization:
(R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID is used as a chiral derivatizing agent for alcohols. It is particularly useful in the field of analytical chemistry, where it can be employed to determine the enantiomeric purity of chiral alcohols. The compound reacts with alcohols to form derivatives that can be easily analyzed and separated using various techniques, such as gas chromatography or high-performance liquid chromatography.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID can be used as a building block or intermediate in the synthesis of various chiral drugs. The compound's unique structure and reactivity make it a valuable component in the development of new pharmaceuticals with improved efficacy and selectivity.
Used in Chemical Synthesis:
(R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID can also be utilized in the synthesis of other chiral compounds, such as chiral ligands, catalysts, and organocatalysts. These compounds are essential in various chemical reactions, particularly in asymmetric synthesis, where they can help achieve high levels of enantioselectivity and improve the overall yield of the desired product.
Used in Research and Development:
Due to its unique properties and potential applications, (R)-3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID is a valuable compound for research and development in various fields, including chemistry, biology, and materials science. Researchers can use this compound to explore new reaction pathways, develop novel synthetic methods, and investigate its potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 121250-04-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,2,5 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 121250-04:
(8*1)+(7*2)+(6*1)+(5*2)+(4*5)+(3*0)+(2*0)+(1*4)=62
62 % 10 = 2
So 121250-04-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H3F3O3/c4-3(5,6)1(7)2(8)9/h1,7H,(H,8,9)/t1-/m1/s1
121250-04-2Relevant articles and documents
Self-disproportionation of enantiomers of isopropyl 3,3,3-(trifluoro)lactate via sublimation: Sublimation rates vs. enantiomeric composition
Yasumoto, Manabu,Ueki, Hisanori,Ono, Taizo,Katagiri, Toshimasa,Soloshonok, Vadim A.
, p. 535 - 539 (2010)
The presented results convincingly demonstrate that self-disproportionation of enantiomers via sublimation is substantially more complex phenomenon then was previously believed. We demonstrate that the racemic form of isopropyl 3,3,3-trifluoro-2-hydroxypr
Enantioselective synthesis of 1,1,1-trifluoroalkan-2-ols by ruthenium- catalyzed hydrogenation
Kuroki, Yoshichika,Asada, Daisuke,Sakamaki, Yuko,Iseki, Katsuhiko
, p. 4603 - 4607 (2007/10/03)
The highly enantioselective synthesis of 1,1,1-trifluoroalkan-2-ols has been achieved by hydrogenating 1,1,1-trifluoroalkan-2-one enol acetates in the presence of chiral ruthenium catalysts. An enol acetate, 2-acetoxy-3,3,3- trifluoro-1-(phenylthio)propen
