12135-22-7 Usage
Description
Palladium hydroxide is a black powder that is enhanced for energy efficiency and possesses unique chemical properties, making it a versatile catalyst in various chemical reactions.
Uses
Used in Organic Chemistry:
Palladium hydroxide is used as a catalyst for arylation reactions, which are crucial for the synthesis of various organic compounds and pharmaceuticals.
Used in Hydrogenolysis:
Palladium hydroxide serves as a nonpyrophoric catalyst for the hydrogenolysis of benzyl-nitrogen and benzyl-oxygen bonds, enabling the selective cleavage of these bonds in organic molecules.
Used in Hydrogenation Reactions:
Palladium hydroxide is utilized as a catalyst in hydrogenation reactions, which are essential for the reduction of various functional groups in organic compounds.
Used in Pharmaceutical Industry:
Palladium hydroxide is used as a catalyst in the synthesis of glycopeptides, which are vital for obtaining antibodies from autoimmune diseases, contributing to the development of treatments for various health conditions.
Flammability and Explosibility
Nonflammable
Check Digit Verification of cas no
The CAS Registry Mumber 12135-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,1,3 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 12135-22:
(7*1)+(6*2)+(5*1)+(4*3)+(3*5)+(2*2)+(1*2)=57
57 % 10 = 7
So 12135-22-7 is a valid CAS Registry Number.
InChI:InChI=1/2H2O.Pd/h2*1H2;/q;;+2/p-2
12135-22-7Relevant articles and documents
Optimization of reductive debenzylation of hexabenzylhexaazaisowurtzitane (the key step for synthesis of HNIW) using response surface methodology
Bayat, Yadollah,Ebrahimi, Heshmat,Fotouhi-Far, Farshad
, p. 1733 - 1738 (2012)
Reductive debenzylation of hexabenzylhexaazaisowurtzitane (HBIW) was carried out using palladium hydroxide deposited on activated carbon catalyst. The catalyst has been characterized using a nitrogen adsorption/desorption isotherm, a hydrogen isotherm, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The synthesized catalyst showed pore sizes larger than 20 A, which are attributed to mesopore structures. A multivariate optimization approach was developed by means of central composite design (CCD) for optimizing reaction conditions. The influence of four variables, including the catalyst to HBIW (1) relative percent, reaction temperature, hydrogen pressure, and acetic anhydride (Ac2O), on the reaction yield was investigated. The results showed that the optimum parameters for reductive debenzylation were 20% (w/w) for catalyst to HBIW (1) percent, 48.5 °C for reaction temperature, 4.25 bar for hydrogen pressure, and 10.9 for Ac2O/HBIW mole ratio. Under these conditions, the reaction yield increased to 73%.