1215-07-2

Basic information

• Product Name: α-Nitrostilbene
• Synonyms: ALPHA-NITROSTILBENE;(1-Nitroethene-1,2-diyl)dibenzene
• CAS NO: 1215-07-2
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.246
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1215-07-2.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-Nitrostilbene(CAS DataBase Reference)
• NIST Chemistry Reference: α-Nitrostilbene(1215-07-2)
• EPA Substance Registry System: α-Nitrostilbene(1215-07-2)

Safety Data

• Hazardous Substances Data: 1215-07-2(Hazardous Substances Data)

Usage

Description

α-Nitrostilbene is an organic compound that serves as an analog of 4-Nitrostilbene. It is characterized by its chemical structure and properties, which have been the subject of recent research due to its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
α-Nitrostilbene is used as an inhibitor for arginine methyltransferase-1 (PRMT1) due to its ability to show inhibitory effects towards this enzyme. This application is significant because PRMT1 plays a crucial role in various cellular processes, and its dysregulation has been linked to several diseases, making α-Nitrostilbene a promising candidate for therapeutic intervention in conditions related to PRMT1 overactivity or misregulation.

Upstream product

• 622-42-4 1-nitro-1-phenylmethane 
• 100-52-7 benzaldehyde 
• 1796-05-0 cis-1,2-dinitrostilbene 
• 116467-21-1 C₁₆H₁₆NO₃S^(1-) 
• 116467-25-5 C₁₆H₁₆NO₂S^(1-) 
• 28531-58-0 (2-oxo-2-phenylethyl)mercury chloride 
• 12413-18-2 phenylnitromethane carbanion 
• 13440-25-0 (+/-)-1,2-dinitro-1,2-diphenylethane 
• 13286-95-8 meso-1,2-dinitro-1,2-diphenylethane 
• 6852-55-7 N-benzylidenepropylamine 
• 67-64-1 acetone 
• 64-17-5 ethanol 
• 110-86-1 pyridine 
• 1689-71-0 2,3-diphenyloxirane 

Downstream Products

• 124645-68-7 (2R,3R)-1-Oxy-3,4-diphenyl-2-((Z)-propenyl)-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 124645-68-7 (2R,3R)-1-Oxy-3,4-diphenyl-2-((E)-propenyl)-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 22020-72-0 triphenylizoxazole 
• 109704-06-5 <1-(1-Acetyl-2-hydroxy-1-propenyl)-2-methyl-4,5-diphenyl-3-pyrrolyl>methylketon 
• 1220140-21-5 diethyl 4,5-diphenyl-1H-pyrazol-3-ylphosphonate 
• 62142-80-7 3,4-diphenyl-1,5-dihydro-2H-pyrrol-2-one 
• 109703-66-4 3-(4-Acetyl-2,3-dihydro-5-methyl-2,3-diphenyl-2-furylimino)-2,4-pentandion 
• 107389-26-4 3-Acetyl-5-aci-nitro-4,5-diphenyl-2-pentanon 
• 4264-27-1 diethyl 2-phenyl-1H-indol-3-yl-3-phosphonate 
• 103549-15-1 N-(α'-nitro-bibenzyl-α-yl)-aniline 
• 144632-59-7 methyl 2-nitro-1,2-diphenyl-3-(1-phenylethyl)hexahydropyrrolizine-7a-carboxylate 
• 79823-40-8 5,6-Dihydro-8,9-dimethoxy-2,3-diphenylpyrrolo<2,1-a>isochinolin-1-carbonsaeure-ethylester 
• 91461-88-0 ((4S,5S)-2-Oxy-3,4-diphenyl-4,5-dihydro-isoxazol-5-yl)-phenyl-methanone 
• 91461-88-0 ((4S,5R)-2-Oxy-3,4-diphenyl-4,5-dihydro-isoxazol-5-yl)-phenyl-methanone 

Relevant articles and documents

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Iron(III) nitrate-induced aerobic and catalytic oxidative cleavage of olefins

Microwave-assisted catalytic oxidative cleavage of olefins using Fe(NO3)3·9H2O under O2 is reported. This reaction system is particularly effective when 9-benzylidene-9H-fluorene derivatives are used as substrates even though they are tri- and tetra-substituted olefins.

In order to iodide is one pot synthesis nitryl source α, β - unsaturated nitro olefin derivatives (by machine translation)

The present invention discloses a one-pot synthesis nitryl source iodide is α, β - unsaturated nitro olefin derivatives, vinyl compounds containing four aryl ferrous (III), iodide and tertiary-butyl hydrogen peroxide in acetonitrile solution system a pot of reaction, generating α, β - unsaturated nitro olefin derivatives; the method to achieve the under mild reaction conditions, high yield with high stereo selectivity of the E synthesis of α, β - unsaturated nitro olefin. (by machine translation)