121518-07-8Relevant articles and documents
Glucopyranosides Derived from Allopurinol and Their Xanthine Oxidase Inhibitory Activity
Jain, S. M.,Kumar, Ashwani,Purnima, Basant,Anand, K. K.,Saxena, Ajit K.,Atal, C. K.
, p. 390 - 393 (2007/10/02)
N1,N5-Bis(α- and β-D-glucopyranosides) (VIa and VIIa), and N1-α-, N2-β- and N5-β-D-glucopyranosides (VIIIa, IXa and Xa) of allopurinol have been prepared by glycosidation of allopurinol via the corresponding bis-trimethylsilyl intermediate and penta-O-acetyl-α-D-glycopyranose in the presence of tin tetrachloride as catalyst, and tested for their xanthine oxidase inhibitory activity in vivo.The structure of these products have been assigned on the basis of their UV, PMR and (13)C NMR spectral data.